The nursing process is part of the Systematization of Nursing Care, it is a care management tool, which is organized in a systematic way and guides the diagnostic decision making, results and intervention of the patients. This study aimed to identify obstacles in the elaboration of a Systematization of Nursing Care, under the perception of nurses. It is an integrative literature review that carried out the synthesis of knowledge and grouping by similarities in thematic categories. The results indicated the categories: implementation / implementation of the Nursing Assistance Systematization: Difficulties Associated with the SAE Practice and, Determining Benefits / Factors for the Implementation / Implementation of the Nursing Assistance Systematization. This was understood as an activity that enables the theoretical knowledge of nurses, which enables them to understand and apply correctly the concepts of nursing theories, and to base their evaluations, decisions and interventions. Therefore, it is necessary to deepen studies and share experiences about the stages that constitute this process of systematization in the various Brazilian hospitals.