Sarcoma de Kaposi retal isolado em paciente portador de HIV e infecção pelo vírus Herpes humano tipo 8: relato de caso

Robert William de Azevedo Bringel; Eric Arcanjo Bringel; Júlia Oliveira de Assis

doi:10.54257/2965-0585.v4.i1.64

Relato de Caso

v. 4 n. 1 (2023)

Sarcoma de Kaposi retal isolado em paciente portador de HIV e infecção pelo vírus Herpes humano tipo 8: relato de caso

Robert William de Azevedo Bringel^▸^▾
Eric Arcanjo Bringel^▸^▾
Júlia Oliveira de Assis^▸^▾

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DOI: https://doi.org/10.54257/2965-0585.v4.i1.64
Enviado: dezembro 28, 2023
Publicado: 2024-05-22

Resumo

O objetivo dos autores é descrever um caso de volumoso Sarcoma de Kaposi (SK) retal isolado, em paciente homossexual, portador de HIV e infecção pelo vírus Herpes humano tipo 8 (HHV 8), com queixas de dor e sangramento retal, demonstrando os achados endoscópicos e desafios no diagnóstico. Os dados foram colhidos do prontuário do paciente, com história clínica, exame físico, acesso aos exames endoscópicos e de imagem, resultados de exames laboratoriais e da patologia. Este é um dos raros relatos de SK retal isolado em paciente com SIDA e coinfecção pelo HHV 8, ressaltando a importância da suspeição e busca ativa em pacientes HIV-positivos com achados endoscópicos relevantes.

Referências

Bishop BN, Lynch DT. Kaposi Sarcoma. 2023 Jun 5. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 30521260.
Simard EP, Pfeiffer RM, Engels EA. Cumulative incidence of cancer among individuals with acquired immunodeficiency syndrome in the United States. Cancer. 2011 Mar 1;117(5):1089-96. doi: 10.1002/cncr.25547. Epub 2010 Oct 19. PMID: 20960504; PMCID: PMC3052856.
Hoffmann C, Sabranski M, Esser S. HIV-Associated Kaposi's Sarcoma. Oncol Res Treat. 2017;40(3):94-98. doi: 10.1159/000455971. Epub 2017 Feb 9. PMID: 28259888.
Begré L, Rohner E, Mbulaiteye SM, Egger M, Bohlius J. Is human herpesvirus 8 infection more common in men than in women? Systematic review and meta-analysis. Int J Cancer. 2016 Aug 15;139(4):776-83. doi: 10.1002/ijc.30129. Epub 2016 Apr 26. PMID: 27062038; PMCID: PMC5563519.
Letang E, Lewis JJ, Bower M, Mosam A, Borok M, Campbell TB, Naniche D, Newsom-Davis T, Shaik F, Fiorillo S, Miro JM, Schellenberg D, Easterbrook PJ. Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma: higher incidence and mortality in Africa than in the UK. AIDS. 2013 Jun 19;27(10):1603-13. doi: 10.1097/QAD.0b013e328360a5a1. PMID: 23462220.
Olanipekun T, Kagbo-Kue S, Egwakhe A, Mayette M, Fransua M, Flood M. Lower Gastrointestinal Kaposi Sarcoma in HIV/AIDS: A Diagnostic Challenge. Gastrointest Tumors. 2019 Aug;6(1-2):51-55. doi: 10.1159/000500140. Epub 2019 Jul 18. PMID: 31602377; PMCID: PMC6738214.
Lee AJ, Brenner L, Mourad B, Monteiro C, Vega KJ, Munoz JC. Gastrointestinal Kaposi's sarcoma: Case report and review of the literature. World J Gastrointest Pharmacol Ther. 2015 Aug 6;6(3):89-95. doi: 10.4292/wjgpt.v6.i3.89. PMID: 26261737; PMCID: PMC4526844.
Imeh M, Gutierrez JO, Bhatija R, Shiza S, Murillo BA, Lubarsky R, Khanna R. Gastrointestinal Kaposi Sarcoma without Dermatological Lesions: A Case Report. Am J Case Rep. 2023 Dec 7;24:e941815. doi: 10.12659/AJCR.941815. PMID: 38060456; PMCID: PMC10711638.
Iftode N, Rădulescu MA, Aramă ȘS, Aramă V. Update on Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) - review. Rom J Intern Med. 2020 Dec 17;58(4):199-208. doi: 10.2478/rjim-2020-0017. PMID: 32681788.
Kumar A, Nautsch D. Kaposi's Sarcoma of the Rectum in a Homosexual Male with HIV-AIDS. ACG Case Rep J. 2016 Dec 21;3(4):e192. doi: 10.14309/crj.2016.165. PMID: 28119943; PMCID: PMC5226188.

Palavras-chave

Sarcoma de Kaposi
Neoplasia do reto
SIDA
Herpesvirus Humano 8

Como Citar

Bringel, R. W. de A., Bringel, E. A., & Assis, J. O. de. (2024). Sarcoma de Kaposi retal isolado em paciente portador de HIV e infecção pelo vírus Herpes humano tipo 8: relato de caso. Revista Científica Do Hospital E Maternidade José Martiniano Alencar, 4(1), 43–47. https://doi.org/10.54257/2965-0585.v4.i1.64

Este trabalho está licenciado sob uma licença Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

[1] Bishop BN, Lynch DT. Kaposi Sarcoma. 2023 Jun 5. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 30521260.

[2] Simard EP, Pfeiffer RM, Engels EA. Cumulative incidence of cancer among individuals with acquired immunodeficiency syndrome in the United States. Cancer. 2011 Mar 1;117(5):1089-96. doi: 10.1002/cncr.25547. Epub 2010 Oct 19. PMID: 20960504; PMCID: PMC3052856.

[3] Hoffmann C, Sabranski M, Esser S. HIV-Associated Kaposi's Sarcoma. Oncol Res Treat. 2017;40(3):94-98. doi: 10.1159/000455971. Epub 2017 Feb 9. PMID: 28259888.

[4] Begré L, Rohner E, Mbulaiteye SM, Egger M, Bohlius J. Is human herpesvirus 8 infection more common in men than in women? Systematic review and meta-analysis. Int J Cancer. 2016 Aug 15;139(4):776-83. doi: 10.1002/ijc.30129. Epub 2016 Apr 26. PMID: 27062038; PMCID: PMC5563519.

[5] Letang E, Lewis JJ, Bower M, Mosam A, Borok M, Campbell TB, Naniche D, Newsom-Davis T, Shaik F, Fiorillo S, Miro JM, Schellenberg D, Easterbrook PJ. Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma: higher incidence and mortality in Africa than in the UK. AIDS. 2013 Jun 19;27(10):1603-13. doi: 10.1097/QAD.0b013e328360a5a1. PMID: 23462220.

[6] Olanipekun T, Kagbo-Kue S, Egwakhe A, Mayette M, Fransua M, Flood M. Lower Gastrointestinal Kaposi Sarcoma in HIV/AIDS: A Diagnostic Challenge. Gastrointest Tumors. 2019 Aug;6(1-2):51-55. doi: 10.1159/000500140. Epub 2019 Jul 18. PMID: 31602377; PMCID: PMC6738214.

[7] Lee AJ, Brenner L, Mourad B, Monteiro C, Vega KJ, Munoz JC. Gastrointestinal Kaposi's sarcoma: Case report and review of the literature. World J Gastrointest Pharmacol Ther. 2015 Aug 6;6(3):89-95. doi: 10.4292/wjgpt.v6.i3.89. PMID: 26261737; PMCID: PMC4526844.

[8] Imeh M, Gutierrez JO, Bhatija R, Shiza S, Murillo BA, Lubarsky R, Khanna R. Gastrointestinal Kaposi Sarcoma without Dermatological Lesions: A Case Report. Am J Case Rep. 2023 Dec 7;24:e941815. doi: 10.12659/AJCR.941815. PMID: 38060456; PMCID: PMC10711638.

[9] Iftode N, Rădulescu MA, Aramă ȘS, Aramă V. Update on Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) - review. Rom J Intern Med. 2020 Dec 17;58(4):199-208. doi: 10.2478/rjim-2020-0017. PMID: 32681788.

[10] Kumar A, Nautsch D. Kaposi's Sarcoma of the Rectum in a Homosexual Male with HIV-AIDS. ACG Case Rep J. 2016 Dec 21;3(4):e192. doi: 10.14309/crj.2016.165. PMID: 28119943; PMCID: PMC5226188.